Charlotte Ling and her research group have studied DNA methylations in the genome of different patient groups with type 2 diabetes. Photo: Kennet Ruona A new study by researchers at Lund University supports the notion that patients with type 2 diabetes should be divided into subgroups and given individualised treatment. The study demonstrates that there are distinct epigenetic differences between

https://www.ludc.lu.se/article/epigenetic-markers-predict-complications-patients-type-2-diabetes - 2025-08-27

Charlotte Ling, Tina Rönn and Karl Bacos carry out research at Lund University Diabetes Centre. They summarise some of the most important advancements within the field of epigenetics and diabetes in a review article. Photo: Petra Olsson Epigenetics has become an important tool for researchers endeavoring to understand the causes and development stages of type 2 diabetes. In the future, epigenetic

https://www.ludc.lu.se/article/epigenetics-can-pave-way-individualised-treatment-type-2-diabetes - 2025-08-27

From left: Ewelina Golec, Ben King and Anna Blom, three of the researchers behind new findings on insulin secretion. Photo: Tove Smeds. Insulin secretion into the bloodstream requires a protein called CD59. New research led by Lund University shows that the two protein variants that are responsible for this function of CD59 are affected in diabetes. The study has been recently published in PNAS. I

https://www.ludc.lu.se/article/newly-discovered-protein-variants-are-key-insulin-secretion - 2025-08-27

Children taking part in the TEDDY study in Sweden have an increased risk of developing type 1 diabetes and are screened for the disease. Research nurse Jessica Melin takes a blood sample from one of the participants. Photograph: Kennet Ruona Why do some people develop type 1 diabetes and others do not? Worldwide, researchers are now collaborating to find the answer to this complex question. Diabet

https://www.ludc.lu.se/article/blood-testing-children-leads-better-understanding-type-1-diabetes - 2025-08-27

Anja Schmidt-Christensen is studying microstructural changes in humans with diabetic kidney disease. She was recently awarded a grant from the Hjelt Diabetes Foundation for her research project. Photo: Petra Olsson Three researchers at Lund University Diabetes Centre (LUDC) have each been awarded a project grant of 47,500 euro by the Hjelt Diabetes Foundation. The aim of all three projects is to i

https://www.ludc.lu.se/article/new-funding-hjelt-diabetes-foundation-improve-understanding-diabetes - 2025-08-27

Enming Zhang is measuring insulin secretion in islets of Langerhans from healthy human donors where the expression of Piezo1 has been blocked. Photograph: Petra Olsson Impaired insulin secretion is closely associated with type 2 diabetes, but the process is not yet fully understood. A new study by researchers at Lund University shows that the Piezo1 ion channel regulates insulin secretion, which m

https://www.ludc.lu.se/article/study-shows-piezo1-ion-channel-plays-important-role-insulin-secretion - 2025-08-27

Flemming Pociot and Søren Brunak from the Scientific Advisory Board were invited to the LUDC retreat recently. Photo: Petra Olsson We were interested to know what our Scientific Advisory Board think about the research currently underway at Lund University Diabetes Centre (LUDC), and invited Flemming Pociot and Søren Brunak from the board to the LUDC retreat in Helsingborg recently. They spent thei

https://www.ludc.lu.se/article/scientific-advisory-board-we-hope-see-more-data-about-subgroups - 2025-08-27

Marju Orho-Melander is one of the lead authors of the article in Nature Communications, which is based in large-scale analyses of faeces and blood samples. Photograph: Petra Olsson A large-scale faeces and blood sample study indicates strong associations between gut bacteria and metabolites in the blood. Among other findings, the research team behind the study has identified new associations betwe

https://www.ludc.lu.se/article/gut-microbiome-research-indicates-new-bacteria-and-metformin-associations - 2025-08-27

Helena Elding Larsson is awarded the Medeon stipend 2022 for her contribution to research into type 1 diabetes. The stipend will be presented during World Diabetes Day Skåne. Photo: Johan Persson Since Helena Elding Larsson began her career as a diabetes researcher and paediatrician, she has seen many improvements in the care of patients with diabetes. Her own research focuses on the prevention of

https://www.ludc.lu.se/article/diabetes-researcher-helena-elding-larsson-wants-prevent-type-1-diabetes-developing - 2025-08-27

Six researchers at Lund University Diabetes Centre (LUDC) were recently awarded grants within medicine and health by the Swedish Research Council. Photograph: Kennet Ruona Six researchers at Lund University Diabetes Centre (LUDC) were recently awarded grants within medicine and health by the Swedish Research Council (Vetenskapsrådet). The six researchers are members of the strategic research area

https://www.ludc.lu.se/article/several-diabetes-researchers-ludc-receive-grants-swedish-research-council - 2025-08-27

Nurse Anna Hellman measures the blood pressure of a participant in a treatment study where researchers are investigating how the hormone vasopressin is affected by how much water we drink. Photo: Kennet Ruona How much water do we need to drink to stay healthy? How do different diets affect our metabolism? Studies of various hormones in the body are providing diabetes researchers with new answers t

https://www.ludc.lu.se/article/learning-more-about-endocrine-system-could-lead-fewer-cases-type-2-diabetes-and-obesity - 2025-08-27

World Diabetes Day in Malmö was all about science. Researchers told the latest on diabetes research from stem cells to diet and the smallest hade the opportunity to becoming scientists - and learn what makes a strawberry a strawberry .  Organisers:Lund University Diabetes Centre, Scania Hospital, Diabetes Society in Malmö/Lund and TEDDY.

https://www.ludc.lu.se/article/world-diabetes-day-malmo-2015 - 2025-08-27

Charlotte Ling has been awarded a Proof of Concept Grant by the European Research Council, ERC, for the further development of research into epigenetics and biomarkers. Photo: Kennet Ruona Professor Charlotte Ling at Lund University Diabetes Centre (LUDC) has been awarded a Proof of Concept Grant by the European Research Council, ERC, for the further development of her successful research on epige

https://www.ludc.lu.se/article/erc-grant-research-diabetes - 2025-08-27

Diabetes researcher Tove Fall is the recipient of the Leif C. Groop award 2023 for outstanding research in the field of molecular epidemiology. Photo: Mikael Wallerstedt Tove Fall became a familiar face during the Covid-19 pandemic when she was often seen in Swedish media talking about the spread and progression of the disease in Sweden. She is also an outstanding diabetes researcher who uses larg

https://www.ludc.lu.se/article/diabetes-researcher-tove-fall-recipient-leif-c-groop-award-2023 - 2025-08-27

Charlotte Ling, Tina Rönn, and Karl Bacos are three of the authors of a new study that has identified an important gene that affects insulin secretion. Photo: Petra Olsson Researchers have identified 395 genes that are differently expressed in people with type 2 diabetes. One of the genes proved to be very strongly associated with impaired insulin secretion. Now, researchers want to investigate if

https://www.ludc.lu.se/article/pax5-gene-strongly-associated-impaired-insulin-secretion-type-2-diabetes - 2025-08-27

First author Daniel E. Coral, LUDC researcher A team of researchers led by Daniel E. Coral and Paul W. Franks at LUDC have used human genetics to do a phenome-wide analysis of the degree of genetic dissimilarity between obesity and type 2 diabetes. Together with colleagues from Dundee and Oxford universities in the UK and the Vanderbilt Genetics Institute in the US, the team recently published the

https://www.ludc.lu.se/article/genetic-driven-approach-defining-two-obesity-profiles-convey-highly-concordant-and-discordant - 2025-08-27

Diabetes researcher Rashmi Prasad has led the research project about subgroups of type 2 diabetes in India. Photograph: Petra Olsson Researchers at Lund University have previously shown that type 1 diabetes and type 2 diabetes can be divided into five subgroups, and that there are genetic differences between the four subgroups relating to type 2 diabetes. A research collaboration between Sweden an

https://www.ludc.lu.se/article/swedish-research-about-different-forms-type-2-diabetes-relevant-indian-people - 2025-08-27

Charlotte Ling’s research group has discovered epigenetic biomarkers that help them understand who will benefit from a common diabetes drug. Photo: Kennet Ruona Precision medicine aims to deliver the right treatment to the right person at the right time. What does this mean for people with type 2 diabetes? Some of the research at Lund University Diabetes Centre (LUDC) focuses on the progression of

https://www.ludc.lu.se/article/epigenetics-and-genetics-help-illustrate-how-diabetes-care-can-be-individualised - 2025-08-27

Isabel Goncalves, Jiangming Sun, and Andreas Edsfeldt studying two atherosclerotic plaques. The study in JACC is based on a close collaboration between clinically active researchers and experts in bioinformatics. Photo: Petra Olsson A common cause of myocardial infarction and stroke is the rupture of atherosclerotic plaques. The exact location of plaque ruptures has previously been unknown, but no

https://www.ludc.lu.se/article/new-discoveries-about-where-atherosclerotic-plaques-rupture-can-lead-preventive-treatments - 2025-08-27

Jiangming Sun studies an atherosclerotic plaque. A goal with his research is to identify dangerous plaques at an early stage. The research project is now awarded a grant by the Hjelt Diabetes Foundation. Photograph: Petra Olsson Every year, the Bo and Kerstin Hjelt Diabetes Foundation awards three diabetes researchers at Lund University Diabetes Centre (LUDC) each a project grant of 47,500 euro. O

https://www.ludc.lu.se/article/type-2-diabetes-researchers-receive-support-hjelt-diabetes-foundation - 2025-08-27